Clinical features and quality of life of patients with idiopathic megacolon

PATIENTS AND METHODS: the retrospective study of clinical features and diagnostic tests results included 81 patients with idiopathic megacolon/megarectum (2004–2022). The diagnosis was confirmed a barium enema, Hirschsprung’s disease excluded based on anorectal manometry (if needed) rectal Swenson biopsy. QoL assessed by IBSQOL questionnaire; symptoms were point scale. RESULTS: quality life in megacolon has most affected energy (emotional physical) physical role (work/main activity). In univariate analysis significant correlation revealed between age, sex, rate defecation without assistance, integral parameters “abdominal discomfort” “defecation difficulties”, duration anamnesis, Wexner constipation scale gut transit time (p < 0,05). same time, presence or absence anal incontinence (leakage), colon rectum sizes (based enema), defecografy compliance test have not correlated QoL. No difference added to conservative treatment operated after. Due multivariate (multiple linear regression) age difficulties” only independent factors life. CONCLUSION: terms life, greatest impact general tone ability perform basic professional activities. Independent that statistically significantly affect assessment are severity abdominal discomfort disorders.